Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

A researcher examines cancer cells under a microscope for an article about pancreatic tumor regression — 14 words.

Spanish researchers achieve full pancreatic tumor regression in a mouse model study

Pancreatic tumor regression achieved in mice marks a rare and significant breakthrough in one of oncology’s most stubborn challenges. Researchers at Spain’s National Cancer Research Centre induced complete disappearance of established pancreatic tumors by reprogramming the tumor microenvironment, allowing the immune system to recognize and destroy cancer cells. Pancreatic cancer kills the vast majority of patients it affects, with a five-year survival rate below 12%, partly because dense tissue surrounding tumors blocks treatment and hides cancer from immune defenses. While mouse results don’t guarantee human success, this proof of concept signals that full regression in this disease is biologically possible.

A researcher reviewing cancer screening data in a global health clinic for an article about cancer death decline

Global cancer deaths peak for the first time and begin a historic decline

Global cancer deaths could peak in 2046, with worldwide mortality finally beginning to fall after decades of relentless rise. The shift builds on real momentum: U.S. age-adjusted cancer death rates already dropped 34% between 1991 and 2023, averting millions of deaths. If the trend holds, it would mark a turning point generations of researchers have worked toward.

Close-up of a researcher examining brain scan imagery for an article about Alzheimer's reversal in mice

American scientists fully reverse Alzheimer’s in mice in a promising study

Alzheimer’s reversal in mice has been achieved by a team of American researchers who eliminated amyloid plaques and tau tangles while restoring measurable memory and spatial reasoning in treated animals. Using precision gene therapy to suppress overactive neurodegeneration pathways, the team reduced brain inflammation and reactivated neurons that had gone functionally silent. The findings matter because no existing treatment reverses Alzheimer’s — they only slow it. What makes this significant is that recovery, not merely stabilization, was observed, challenging longstanding assumptions about irreversible brain damage and strengthening the case that neuroplasticity could become a realistic therapeutic target.

A young child eating a nutritious meal in a sunlit community setting for an article about child malnutrition eliminated

Humanity effectively eliminates child malnutrition for the first time in history

Child malnutrition could be effectively eliminated as a global public health emergency by 2041, according to a projection from the UN and World Food Programme. Global stunting rates in children under five sat near 22% in the mid-2020s, and sustained progress on the first 1,000 days of life is what makes the path credible. If it holds, hundreds of millions of children would grow up with futures their grandparents couldn’t have imagined.

A community health worker treats a child in a rural village for an article about neglected tropical diseases

Humanity cuts neglected tropical diseases to less than 1% of 2000 levels

Neglected tropical diseases could fall below 1% of their year-2000 levels by 2041, the WHO projects, with five diseases fully eradicated and twelve others eliminated as public health problems. The shift began with the 2021 roadmap’s pivot toward country-led, community-rooted care. If it holds, it would mark one of the most sweeping health gains in human history.

Earth's atmosphere glowing blue from space for an article about ozone layer recovery, for article on Montreal Protocol ozone layer, for article on HCFC atmospheric decline

Global ozone layer reaches 1980 levels for the first time in decades

Earth’s ozone layer could return to 1980 levels by 2040, marking the first time a planet-scale atmospheric system damaged by industry has been measurably healed. Emissions of ozone-depleting chemicals have already fallen more than 99% from their peak, tracking the UN’s 2023 recovery projection. If it holds, it’s proof that coordinated global action really can mend what we’ve broken.

Cooling towers of a coal power plant at sunset for an article about coal phase-out

Humanity shuts down its last coal-fired power plant

Coal-fired power could vanish worldwide by 2040, when the last plant — a 74-year-old facility in China’s Shanxi Province — is projected to go dark. Global coal capacity already peaked around 2022, as solar and wind became the cheapest new electricity in history. If the trend holds, cleaner air and roughly 800,000 fewer pollution deaths each year would follow.

A doctor reviewing patient records in a bright clinic for an article about U.S. cancer survival rates

More than 7 in 10 U.S. cancer patients now survive five years after diagnosis

Cancer survival rates in the United States have crossed 70% for the first time in recorded medical history, meaning the majority of the roughly 2 million Americans diagnosed each year will be alive five years later. Up from approximately 50% in the 1970s, this milestone reflects decades of progress in early detection, immunotherapy, targeted treatments, and survivorship care. More than 4 million cancer deaths were averted between 1991 and 2022. Critically, significant gaps persist by race, cancer type, and geography, making equity the defining challenge of what comes next.