Annual jab for HIV protection passes trial hurdle
A once-yearly HIV prevention shot has just cleared its first safety trial, with the drug lenacapavir still detectable in participants’ bodies a full 56 weeks after a single injection. That’s a hopeful sign for people who find daily prevention pills hard to maintain — whether because of stigma, unstable housing, or simply the grind of remembering. Earlier trials of twice-yearly lenacapavir already showed striking results, and researchers are now testing whether one shot a year could work just as well. With nearly 40 million people living with HIV globally, a prevention tool this simple could reshape what protection looks like — especially for communities where daily medication has never been realistic.








