Technology & innovation

This archive covers technology and innovation breakthroughs that improve lives, protect the environment, and expand human possibility. From medical devices to clean energy tools, the stories here focus on what’s working and who’s making it happen.

Pills and syringe, for article on fentanyl vaccine human trials

Scientists preparing first human trials for vaccines that block the effects of deadly opioids

Fentanyl vaccines are heading into their first human trials, with Phase 1 testing set to begin in early 2024 at Columbia University. Developed by researchers at the University of Montana and University of Washington, the vaccines train the immune system to grab fentanyl molecules in the bloodstream, like a sponge, before they can reach the brain. That means no high, and no slowed breathing, which is what makes overdoses fatal. The team is especially focused on people in the first two years of recovery, when relapse risk is highest. If it works, this could become a powerful new tool in a crisis that has demanded every bit of compassion and ingenuity we can offer.

Model of a heart, for article on muvalaplin Lp(a) cholesterol

World-first drug lowers genetic form of “bad cholesterol” by up to 65%

Muvalaplin, a new pill from researchers at Monash University, lowered a dangerous genetic form of cholesterol by up to 65% in just two weeks during early trials. The drug targets lipoprotein(a), or Lp(a), a stickier cousin of LDL cholesterol that’s been called a “silent killer” because diet, exercise, and statins can’t touch it. Roughly one in five people worldwide carry elevated Lp(a), inherited risk they’ve long been told there’s nothing to do about. That muvalaplin works as a simple oral tablet, not an injection, could make it widely accessible if larger trials succeed. For global heart health, it’s a hopeful sign that even risks written into our DNA may not be the final word.

Virtual reality or cyberspace concept: digital human or robot head, for article on brain-computer interface

Paralyzed woman able to ‘speak’ through digital avatar in world first

A digital avatar has given a paralyzed woman her voice back — speaking at 78 words per minute, more than five times faster than the eye-tracking system she relied on before. Ann, who had a brainstem stroke 18 years ago, worked with UCSF researchers to train an AI to read brain signals from electrodes resting on her brain’s surface. The avatar speaks in a voice reconstructed from her wedding video, complete with facial expressions like smiles and frowns. There are real limits — the system still misreads words about a quarter of the time — but for millions living with ALS, locked-in syndrome, or severe stroke, this points toward a future where losing a voice no longer means losing a self.

Wind turbine, for article on offshore wind turbine

World’s largest wind turbine is now fully operational and connected off coast of China

A single wind turbine off China’s Fujian coast can now power roughly 36,000 homes — and it’s the largest ever connected to a grid. The MySE 16-260 stretches 260 meters across, wider than the Eiffel Tower is tall, with each rotation generating up to 34.2 kilowatt-hours of clean electricity. It’s built to withstand winds of 287 km/h, which matters in a stretch of sea where near-gale conditions blow more than 200 days a year. An 18-megawatt machine is already in the works, hinting at how fast this ceiling keeps rising. Each leap in turbine size makes offshore wind cheaper and more credible as a backbone of the clean energy transition worldwide.

CalTech Space Solar array, for article on space solar power

World-first space solar demonstration beams power from orbit to Earth

Space-based solar power just crossed from theory into reality: a Caltech team has, for the first time, beamed energy from orbit down to a receiver on Earth. The signal arrived at a rooftop in Pasadena exactly when, where, and at the frequency engineers predicted — proof that the precision needed for a future full-scale array is achievable. The demonstrator weighed just 50 kilograms and used flexible, lightweight arrays never before flown for this purpose. The eventual vision is enormous and far from cheap, but the appeal is simple: panels in space see no night and no clouds. If this technology matures, clean power could one day reach communities far beyond the grid’s reach.