Technology & innovation

This archive covers technology and innovation breakthroughs that improve lives, protect the environment, and expand human possibility. From medical devices to clean energy tools, the stories here focus on what’s working and who’s making it happen.

Chromosomes, for article on CRISPR gene therapy hereditary angioedema

Gene therapy hailed as ‘medical magic wand’ for hereditary swelling disorder

CRISPR gene editing has freed ten patients with hereditary angioedema from the sudden, sometimes life-threatening swelling attacks that shaped their daily lives, with several remaining attack-free for 18 months and counting after a single infusion. The therapy works by switching off a gene in liver cells, stopping the painful chain reaction at its source rather than just managing symptoms. One participant who used to have attacks every three weeks has needed no medication since. Doctors are now recruiting for a phase-three trial, building on the same Nobel-winning technology that recently produced an approved cure for sickle cell disease. For a rare condition long defined by unpredictability and fear, it’s a glimpse of what gene editing could mean for millions living with inherited illness worldwide.

Person having blood drawn, for article on Alzheimer's blood test

Breakthrough Alzheimer’s blood test could detect disease 15 years before symptoms emerge

A simple Alzheimer’s blood test trialed in Sweden can detect the disease’s biological signs up to 15 years before symptoms appear, matching the accuracy of a spinal tap in a study of 786 people. The test measures p-tau217, a protein that builds up in the blood as Alzheimer’s-related changes unfold in the brain. Researchers suggest it could one day be as routine as a cholesterol check for anyone over 50, replacing painful lumbar punctures and hard-to-access specialist scans. With one in three people born in the U.K. today expected to develop dementia, catching the disease early — while there’s still time to intervene — could transform how the world confronts one of its most feared illnesses.

Person receiving shot in the arm

Cancer vaccine with minimal side effects nearing Phase 3 clinical trials

The vaccine- developed by Dr. Thomas Wagner of U.S.-based Orbis Health Solutions – has already been tested in hundreds of patients with advanced forms of melanoma in Phase 2 clinical trials. The most recent data showed nearly 95% of people given only the vaccine were still alive three years after starting treatment and 64% were still disease-free. Among the most advanced forms of melanoma, disease-free survival after three years for people with stage III disease was 60% in the vaccine-only group, compared to about 39% in the placebo group.

Artist's concept of a solar power satellite in place, for article on space solar power

First ever space-to-Earth solar power mission succeeds

Space-based solar power just cleared a milestone scientists have been chasing since the 1970s: a Caltech satellite spent a year in orbit, collected sunlight, and beamed it wirelessly back to a ground receiver on Earth. The SSPD-1 mission completed all three of its planned experiments, including testing an origami-inspired panel that unfolds without hinges and a purpose-built microwave transmitter. The appeal is simple — above the atmosphere, the Sun never sets, no clouds get in the way, and power could flow around the clock. Caltech’s team is honest that commercial-scale space solar is still years off, with cost and radiation durability to solve. But moving this idea from whiteboard to working demonstration brings humanity a real step closer to truly continuous clean energy.

Cancer cells, for article on multi-cancer blood test

New protein test can detect 18 early stage cancers, scientists say

A new blood test can screen for 18 different cancers at once — covering every major organ in the body — using a single ordinary blood draw. Researchers at U.S. biotech firm Novelna found the test caught 93% of earliest-stage cancers in male samples and 84% in female samples, while also pinpointing which organ the cancer came from in more than 80% of cases. Instead of hunting for tumor DNA, the team analyzed proteins in blood plasma, picking up faint signals before a tumor does visible damage. Larger studies are still needed before it reaches clinics, but a cheap, accurate, broad screening tool would be a quiet revolution for global health — especially in places where late diagnosis is still the norm.

House in the snow

Leading heat pump manufacturers develop next-generation prototypes to withstand subfreezing weather

The U.S. Department of Energy has announced that four additional heat pump manufacturers successfully produced heat pump prototypes as part of the Residential Cold Climate Heat Pump (CCHP) Technology Challenge. Launched in 2021, this initiative brings together public and private sector stakeholders to address technical challenges and market barriers to adopting next-generation cold-climate heat pumps—a key clean energy technology that can potentially save households $500 a year or more on their utility bills while also slashing harmful carbon emissions.

Molecule of the human hormone glucagon

Australian scientists regenerate diabetics’ damaged cells to produce insulin

For many years, research has focused on identifying novel therapies that stimulate beta-cell growth and function to restore insulin production in type 1 diabetics. Now, researchers at the Baker Heart and Diabetes Institute in Melbourne have brought us a step closer to making this a reality, regenerating damaged pancreatic cells so they can produce insulin and functionally respond to blood glucose levels. The novel therapeutic approach has the potential to become the first disease-modifying treatment for type 1 diabetes.