Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

Newborn baby being held, for article on spina bifida treatment

World-first stem cell therapy trial treats spina bifida before birth

Spina bifida causes nerve damage that accumulates in the womb, and until now, medicine could only respond after that damage was done. A clinical trial at UC Davis Health is changing that window, applying a stem cell patch directly to a fetus’s spine during pregnancy to support repair before birth. The first baby treated was expected to arrive with leg paralysis — instead, she was kicking and wiggling her toes. If results hold across all 35 enrolled patients, this could establish a genuinely new standard of care for a condition that currently offers families very little hope.

Injecting vaccine, for article on India HPV vaccine

Indian company develops country’s first HPV vaccine

CERVAVAC, India’s first homegrown cervical cancer vaccine, is priced at just $2.50 to $5.00 per dose — a fraction of what HPV vaccines have cost in wealthy countries for nearly two decades. Developed by the Serum Institute of India, it protects against the HPV strains responsible for the majority of cervical cancers worldwide, and the company aims to produce around 200 million doses in its first two years. Cervical cancer is almost entirely preventable, yet it still kills hundreds of thousands of women each year, mostly in lower-income countries where vaccines have been priced out of reach. An affordable, locally made option doesn’t just change the math for India — it points toward a future where health tools belong to the people who need them most.

Female scientist pipetting colored chemicals into a tube, for article on CAR T-cell therapy

Scientists hail autoimmune disease therapy breakthrough

Lupus remission in all five patients — that’s the striking result from a small German trial using CAR T-cell therapy, a treatment originally developed for blood cancers. Doctors collected each patient’s own T-cells, reprogrammed them to clear out the malfunctioning B cells driving the disease, and reinfused them. Months later, the patients’ immune systems had essentially rebooted: new B cells grew back, but they no longer attacked the body. None have needed lupus medication since. The lead researcher believes the same approach could help people with rheumatoid arthritis, multiple sclerosis, and other autoimmune conditions — opening a hopeful new chapter for millions worldwide who have long managed their illness without ever truly being free of it.

A village in Togo, for article on neglected tropical diseases

Togo achieves ‘major feat’ of eliminating four neglected tropical diseases

Togo’s elimination of four neglected tropical diseases is a powerful proof of concept for what sustained political will can achieve in global health. These diseases — which still affect roughly 1.7 billion people worldwide — trap communities in cycles of poverty and disability, yet Togo wiped out all four within eleven years. The WHO called it a model for the entire continent, and with 46 countries having now eliminated at least one NTD, momentum is clearly building. Togo shows the world’s 2030 elimination goal is genuinely within reach.