Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

Patient with IV, for article on primary bone cancer drug

Breakthrough drug works against all the main types of primary bone cancer

Bone cancer research has taken a meaningful step forward, with scientists identifying a single drug candidate that shows activity across all the major types of primary bone cancer — a group of diseases that have long resisted a unified treatment approach. Because these cancers disproportionately affect children and young people, the stakes are especially high. The compound appears to target something the different subtypes share biologically, which could open new research directions well beyond this one discovery. For pediatric cancer medicine, that kind of insight builds the foundation treatments are eventually made from.\n\nWord count: 88

Scientist examines the result of a plaque assay, for article on gene therapy cure MLD

Researchers cure toddler of deadly metachromatic leukodystrophy (MLD) for first time in history

Gene therapy has cured 19-month-old Teddi Shaw of metachromatic leukodystrophy, making her the first NHS patient treated for this rare, fatal nervous system disease. After a single infusion of Libmeldy at Royal Manchester Children’s Hospital, she’s now running around, chattering away, and showing no signs of the illness that typically kills children before age eight. The treatment works by correcting a faulty gene in the child’s own stem cells, eliminating the disease at its root rather than managing it. Her family’s joy is tempered by grief — Teddi’s older sister was diagnosed too late for the therapy to help, fueling calls for newborn screening. It’s a glimpse of medicine’s next era: one-time cures for inherited conditions, if access and early detection can keep pace.