Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

Ghanaian child carrying load on head, for article on R21 malaria vaccine

Ghana first country to approve ‘world-changer’ malaria vaccine

Ghana’s approval of the R21 malaria vaccine — the first anywhere in the world — clears the way for children as young as five months to be protected against a disease that kills roughly 620,000 people every year, mostly young kids in Africa. Developed at Oxford’s Jenner Institute, R21 showed up to 80% effectiveness in early trials and is expected to cost just a couple of dollars per dose. The Serum Institute of India is preparing to produce up to 200 million doses a year, with a factory rising in Accra so supply stays close to home. After a century of scientific near-misses, an African regulator stepped forward and said: this one is ready.

Narcan nasal spray, for article on OTC naloxone

U.S. FDA approves over-the-counter sale of overdose reversal drug Narcan

Over-the-counter Narcan is now a reality: the FDA cleared the 4 mg naloxone nasal spray for sale at pharmacies, convenience stores, and other retailers without a prescription — the first opioid overdose reversal drug ever to earn that status in the U.S. The medication works within minutes to restore breathing, and it’s safe enough that any bystander can use it, no medical training required. For years, harm reduction workers quietly distributed naloxone in their communities, knowing how much it mattered; this decision finally meets them where they’ve been standing. Putting a life-saving tool on the same shelf as aspirin won’t end the overdose crisis on its own, but it’s a powerful reminder that expanding access — trusting ordinary people to help each other — is how public health movements actually save lives.

Patient with IV, for article on primary bone cancer drug

Breakthrough drug works against all the main types of primary bone cancer

Bone cancer research has taken a meaningful step forward, with scientists identifying a single drug candidate that shows activity across all the major types of primary bone cancer — a group of diseases that have long resisted a unified treatment approach. Because these cancers disproportionately affect children and young people, the stakes are especially high. The compound appears to target something the different subtypes share biologically, which could open new research directions well beyond this one discovery. For pediatric cancer medicine, that kind of insight builds the foundation treatments are eventually made from.\n\nWord count: 88

Scientist examines the result of a plaque assay, for article on gene therapy cure MLD

Researchers cure toddler of deadly metachromatic leukodystrophy (MLD) for first time in history

Gene therapy has cured 19-month-old Teddi Shaw of metachromatic leukodystrophy, making her the first NHS patient treated for this rare, fatal nervous system disease. After a single infusion of Libmeldy at Royal Manchester Children’s Hospital, she’s now running around, chattering away, and showing no signs of the illness that typically kills children before age eight. The treatment works by correcting a faulty gene in the child’s own stem cells, eliminating the disease at its root rather than managing it. Her family’s joy is tempered by grief — Teddi’s older sister was diagnosed too late for the therapy to help, fueling calls for newborn screening. It’s a glimpse of medicine’s next era: one-time cures for inherited conditions, if access and early detection can keep pace.