Public health & disease

Credit cards in front of laptop

United States to ban medical debt from credit reports

In a sweeping change that could improve millions of Americans’ ability to own a home or buy a car, the Biden administration proposed a rule to ban medical debt from credit reports. The rule, announced by Vice President Kamala Harris and Consumer Financial Protection Bureau Director Rohit Chopra, comes as President Joe Biden beefs up his efforts to persuade Americans his administration is lowering costs, a chief concern for voters in the upcoming election.

Sick woman

U.K. researchers identify and treat major cause of inflammatory bowel disease

For the first time, a major trigger in inflammatory bowel disease (IBD) and related conditions has been identified, and existing drugs can stamp it out, in what scientists call a “massive step” in successfully treating these debilitating chronic conditions. Researchers at the Francis Crick Institute, in collaboration with University College London (UCL) and Imperial College London (ICL), have uncovered a problem gene enhancer that stimulates action along a specific biological pathway that causes IBD inflammation.

Tetanus vaccination

Global deaths from tetanus have been reduced massively since 1990s

Tetanus is a bacterial disease that causes paralysis and can lead to death. Globally, it was estimated to kill more than 250,000 people each year in the early 1990s. Most of these deaths were in children. By 2019, annual deaths had fallen to less than 35,000. The rollout of the combined vaccine against diphtheria, tetanus, and pertussis among children has been crucial in driving this.

X-ray image of the intestine

New bowel cancer drug is found to be 100% effective

An immunotherapy drug could spare bowel cancer patients the need for surgery and chemotherapy after results showed it was effective in 100% of cases. Jemperli from British pharmaceutical company GSK showed “unprecedented results”, the firm said, with no evidence of disease in all patients treated. The data showed all 42 patients in a trial led by Memorial Sloan Kettering Cancer Center in the U.S. had a complete response to treatment, with no evidence of tumors on scans.

Contraceptives

Free contraception initiative helps Finland reduce teenage abortions by 66%

The number of abortions among women under 20 rose during the 1990s in Finland, leading the Nordic country to make morning-after pills available without prescription from 15 years of age and sexual education compulsory in all schools. As a result, the number of abortions fell 66% to 722 in 2023 from 2,144 in 2000 among all teenagers aged 19 or younger in Finland, while the drop was even steeper at 78% among those under 18 in the same period.

Holding breast cancer ribbon

New blood test can predict breast cancer return

An “ultra-sensitive” new blood test developed and tested by Institute of Cancer Research (ICR) London can predict if breast cancer will return years before the disease shows up on scans, researchers say. It picks up traces of a tumor’s DNA before a full relapse and was found to be 100% accurate at predicting which patients would see their cancer return. It is hoped that the test can allow treatment to start earlier and improve survival rates.

A researcher handling a vaccine vial in a clinical lab for an article about cancer vaccine trials

NHS launches world-first cancer vaccine matchmaking program in England

Cancer vaccine trials are now being fast-tracked through a landmark NHS program in England that matches patients with personalized mRNA vaccines built around their individual tumors. The Cancer Vaccine Launch Pad, operating across 30 hospitals, uses the same mRNA technology behind COVID-19 vaccines to design custom treatments targeting each patient’s unique cancer mutations. The program aims to eliminate remaining cancer cells after surgery before they can return. Early immune response data is encouraging, and a 2024 trial showed a 44% reduction in melanoma recurrence when similar vaccines were combined with immunotherapy.

Aral Sea time lapse 1989 2014

Uzbekistan plants millions of acres of forest where the Aral Sea once lay

Instead of trying to restore what used to be the world’s third largest lake, officials from the Uzbekistan Forestry Agency and locals are trying to plant a new forest where it once rested. The main purpose of the afforestation project it to curb the harmful sandstorms and improve the ecosystem by planting desert-tolerant plants. The initiative has so far planted 4.2 million acres of forest, with up to 494,000 acres of new forest planned for 2024.

A neuron or nerve cell is an electrically excitable cell

Breakthrough synapse-regenerating ALS pill moves to phase 2 human trials

Spinogenix, a clinical-stage biopharmaceutical company based in California, has developed SPG302, a unique once-a-day pill that regenerates the gaps, called synapses, between neurons to restore communication in ALS patients. Following promising results from clinical trials to evaluate the drug’s safety, the FDA has approved the company’s Investigational New Drug application, paving the way for further trials and a possible watershed moment in the treatment of the fatal disease.

Good news for public health

HIV transmissions in the U.S. dropped 12% between 2018 and 2002

According to recent data from the Centers for Disease Control and Prevention (CDC) HIV Surveillance Supplemental Report, the largest decrease in HIV infections from 2018 to 2022 was among men ages 13 to 24, where HIV infections decreased by 30%. In another recent report, the CDC found that over 80% of people diagnosed with HIV had access to care within one month of diagnosis. Furthermore, 65% had achieved viral suppression in 2022.