Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

A neuron or nerve cell is an electrically excitable cell, for article on ALS synapse-regenerating pill

Breakthrough synapse-regenerating ALS pill moves to phase 2 human trials

A once-daily ALS pill designed to rebuild neural connections — not just slow their loss — has cleared FDA approval to begin Phase 2 trials, with patients across the U.S. starting doses in April 2024. SPG302 works on synapses, the tiny junctions where neurons talk to each other, which start vanishing before motor neurons themselves die. Every ALS drug currently on the market aims to slow decline; this one is being tested for whether it can actually help recover lost function. For the roughly 30,000 Americans living with ALS, that’s a genuinely different question to be asking. If it works, it could reshape how researchers approach neurodegenerative disease far beyond ALS.

Good news for public health, for article on CAB-LA HIV prevention, for article on lenacapavir HIV prevention, for article on HIV infections in young men

HIV transmissions in the U.S. dropped 12% between 2018 and 2002

HIV infections among young men in the U.S. dropped 30% between 2018 and 2022, the steepest decline of any age group in the latest CDC surveillance data. Researchers credit expanded testing, faster connection to treatment, and the growing reach of PrEP — a daily pill that cuts transmission risk by up to 99% when taken consistently. The South, long carrying the heaviest HIV burden in the country, saw the largest regional drop, and Black men experienced an 18% decline. Gaps remain, especially for transgender women and Latino gay men, but the news from this generation is genuinely hopeful: when prevention tools reach people early, they work. It’s a glimpse of what ending the epidemic could actually look like.

Packages of diapers, for article on Medicaid diaper coverage

Tennessee to become the first U.S. state to provide some children’s diapers

Free diapers through Medicaid are coming to Tennessee this August, with families receiving 100 a month for every child under two. It’s the first program of its kind in the country, and advocates expect it to deliver close to 100 million diapers a year to families who need them. The need is real: the National Diaper Bank Network found that 92% of Tennessee families receiving diaper assistance are working parents who still can’t afford enough. Local diaper banks helped lay the groundwork, and they’ll keep serving families the program doesn’t reach. Tennessee’s approach offers a tested path other states can follow, turning a quiet daily struggle into something a community can actually solve together.

Person touching pregnant belly with hands forming a heart, for article on LGBTQ+ fertility coverage

Aetna agrees to provide equal fertility coverage for LGBTQ+ people in the U.S. in landmark settlement

LGBTQ+ couples who were charged a “queer tax” of up to $100,000 for fertility treatment just won a major shift at Aetna, including a $2 million fund to reimburse families who paid out of pocket. The settlement ends a policy that required same-sex couples to fund a year of treatments themselves before coverage kicked in, while heterosexual couples qualified after a simple conversation. It started with Emma Goidel and Ilana Caplan, who drained their savings through multiple rounds of IUI and IVF before suing under the Affordable Care Act’s ban on sex discrimination in health care. Their win creates a template other insurers can follow, and a legal path other families can walk, toward fertility care that treats every family as worth building.

A rainforest river winding through dense green jungle in Suriname for an article about Suriname malaria-free certification, for article on dual-insecticide bed nets

New types of mosquito bed nets could cut malaria risk by up to half, trial finds

New mosquito bed nets cut malaria transmission by 20 to 50 percent in a major trial across 17 African countries, offering a real answer to the growing problem of insecticide resistance. The nets pair the standard pyrethroid coating with a second insecticide that hits mosquitoes through a different biological pathway, so the ones that used to shrug off treated nets no longer can. At under three dollars each, they cost about the same as the older versions they’re replacing. Paired with the malaria vaccine now rolling out across Africa, these nets are part of a layered defense that could meaningfully shift the trajectory of a disease that still kills hundreds of thousands of people every year.

Water flowing from faucet, for article on PFAS drinking water limits

U.S. Environmental Protection Agency announces first-ever national regulations for “forever chemicals” in drinking water

PFAS drinking water protections are now federal law, with the EPA setting the first-ever national limits on six “forever chemicals” found in tap water across the country. The rules are expected to reduce exposure for around 100 million Americans and will require roughly 6 to 10 percent of public water systems to upgrade testing and treatment. To help with the lift, $1 billion in federal funding is immediately available to states, with priority for the communities — often low-income and disproportionately communities of color — that have carried the heaviest contamination. After decades of industry resistance and slow-moving science, a binding national standard signals that public health can still win out, and offers a template for confronting the thousands of PFAS compounds still unregulated.

A medical professional drawing blood from a patient's arm for an article about blood tests for dementia, for article on dementia blood test

U.K. launches blood tests for dementia in landmark five-year trial

Dementia blood tests are now being offered at more than 50 memory clinics across the U.K., in a landmark five-year trial aiming to transform how the disease is detected. Led by researchers at Oxford and University College London, the study will screen approximately 5,000 volunteers for protein biomarkers linked to Alzheimer’s and other forms of dementia. Currently, around one in three people with dementia in England has never received a formal diagnosis, and painful, slow pathways mean some patients wait up to four years for results. Earlier detection could connect patients to newer treatments that work best in the disease’s earliest stages.

Elderly person smiling, for article on global life expectancy gains

Global life expectancy increased by 6.2 years between 1990 and 2021

Global life expectancy rose by 6.2 years between 1990 and 2021, according to a sweeping Lancet study built from over 607 billion estimates by researchers at the Institute for Health Metrics and Evaluation. The biggest leap came in Eastern sub-Saharan Africa, where people gained 10.7 years of life, largely thanks to clean water, vaccines, and oral rehydration therapy beating back diarrheal diseases. Steep drops in lower respiratory infections, stroke, and heart disease added further years almost everywhere. The pandemic set things back, but the deeper story is hopeful: targeted public health investment works at scale, and extending those same tools to every country is now the defining frontier of global health.

Mushrooms, for article on psilocybin public opinion

Nearly 9 in 10 Americans now think using psilocybin is ‘morally positive,’ in dramatic shift in public opinion

Supervised psilocybin therapy just got a remarkable vote of confidence: in a new peer-reviewed survey of 795 U.S. adults, 91% of liberals and 86% of conservatives called its use for psychiatric treatment morally acceptable. That’s the kind of bipartisan agreement you almost never see anymore. Researchers from Oxford, Yale, Johns Hopkins, and Granada also found that strong majorities approved of psilocybin to enhance well-being in healthy people, not just to treat illness. The authors suggest compassion-based values help explain the consensus across political lines. As more states move toward legal, supervised psilocybin services, this quiet agreement among Americans hints at a broader, more humane shift in how societies might soon approach mental health.

Milky Way arching over dark desert sagebrush landscape for an article about Oregon Outback dark sky sanctuary, for article on dark sky sanctuary

Oregon outback becomes world’s largest dark sky sanctuary at 2.5 million acres

The Oregon Outback International Dark Sky Sanctuary has become the largest dark sky sanctuary on Earth, covering 2.5 million acres of southeastern Oregon’s Lake County after receiving official certification from DarkSky International. The designation protects skies already considered among the darkest in the world, with nearly 1.7 million acres managed by the Bureau of Land Management under commitments for ongoing monitoring and lighting improvements. Beyond stargazing, the protection matters for wildlife along the Pacific Flyway and species like bighorn sheep and sage grouse that depend on undisturbed terrain. Organizers hope the sanctuary could eventually expand to over 11 million acres.