Public health & disease

South Korean flags

‘Major milestone’ immunization campaign begins in North Korea with support of UNICEF

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More than 800,000 children and 120,000 pregnant women will be vaccinated in a nationwide campaign launched on Monday by the Government of the Democratic People’s Republic of Korea (DPRK) with the support of the UN Children’s Fund (UNICEF). Over four million doses of essential vaccines — including Pentavalent, Measles-Rubella (MR), Tetanus-Diphtheria, BCG, Hepatitis B, and Inactivated Poliovirus Vaccine (IPV) — were delivered to the DPRK in July to kickstart this comprehensive catch-up effort.

Person touching pregnant belly with hands forming a heart

Aetna to start covering IUI in the U.S.

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Medical insurance company Aetna just announced that it’s going to be providing additional fertility coverage, specifically offering intrauterine insemination (IUI), to all policyholders regardless of sexual orientation or whether they’re partnered. This comes after a settlement agreement from a lawsuit earlier this year which stated that Aetna has to provide such care for LGBTQ+ people. The case, Goidel et al. v. Aetna, was filed in September 2021 and only came to a resolution in May after years of waiting and legal battles.

A medical researcher in a laboratory examining vials for an article about mRNA lung cancer vaccine

World’s first mRNA lung cancer vaccine enters human trials in seven countries

By / / Good News For Humankind

A landmark mRNA lung cancer vaccine is now being tested in human patients for the first time, marking a historic milestone in cancer treatment. BNT116, developed by BioNTech, uses the same messenger RNA technology behind COVID-19 vaccines to train the immune system to recognize and destroy non-small cell lung cancer cells. The phase 1 trial spans 34 sites across seven countries, with roughly 130 patients enrolled. Unlike chemotherapy, this approach targets only tumor cells, potentially offering a more precise and lasting defense against the world’s deadliest cancer, which kills 1.8 million people annually.

Honeycomb

Manuka honey reduces breast cancer cell growth by 84% in preliminary studies

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Manuka honey is produced from the nectar collected by honey bees when they pollinate the mānuka, a species of tea tree indigenous to New Zealand and southeast Australia. Now, preliminary studies by researchers at UCLA have found that this nutraceutical might aid in breast cancer prevention and treatment. The honey-treated mice showed significantly suppressed tumor growth compared to controls. Overall, it inhibited the growth and progression of an established human breast cancer tumor by 84% without affecting healthy cells.

MIT naloxone sensor implant

MIT scientists reverse opioid overdoses with ‘Narcan sensor’ implanted under skin

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In 2023, more than 100,000 Americans died from opioid overdoses. The most effective way to save someone who has overdosed is to administer a drug called naloxone, but help can’t always reach the person in time. Researchers at MIT and Brigham and Women’s Hospital have developed a new device to address this problem. The device, about the size of a stick of gum, can be implanted under the skin. When it determines that an overdose has occurred, it rapidly pumps out a dose of naloxone.

Medications

The U.S. negotiates Medicare drug price cuts that will save billions for U.S. citizens

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The United States has negotiated down the prices of 10 top-selling prescription drugs used by Medicare by as much as 79%, hoping to save $6 billion in the first year as part of a plan hailed on Thursday by President Joe Biden with the aim to ease anger about high prices ahead of November elections. Biden’s signature Inflation Reduction Act, signed into law in 2022, was the first to allow Medicare to negotiate prices for some of the most costly drugs that the program covers for 66 million people. The new prices will go into effect in 2026.

Vials of blood

U.S. Food and Drug Administration approves blood test to screen for colon cancer

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The test, known as Shield, isn’t meant to replace colonoscopies, but is generating enthusiasm among doctors who say it has the potential to boost the dismal rate of screenings for the second-highest cause of cancer death in the United States. Shield has previously been available to doctors as a screening tool, at an out-of-pocket cost of $895. With the FDA approval, Medicare and private insurance companies are much more likely to cover the cost of the blood test, making it more widely accessible for patients.

Good news for public health

New twice-yearly shot to prevent HIV achieves 100% success rate in late-stage trial

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In this double-blind, randomized study of 5,300 cisgender women in South Africa and Uganda, 2,134 got the injection and the others took one of two types of daily PrEP pills. The trial from California-based company Gilead Sciences began on August 2021 and, so far, not a single woman who received the injections has contracted HIV. The participants who received either of the oral PrEP options, Truvada and Descovy, had infection rates of about 2% — consistent with the infection rates of oral PrEP in other clinical trials.

Mouse

Japanese scientists reverse Alzheimer’s synapse damage in mice

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Scientists from the Okinawa Institute of Science and Technology say they have reversed the signs of Alzheimer’s disease in lab mice by restoring the healthy function of synapses, critical parts of neurons that shoot chemical messages to other neurons. If the treatment successfully survives the gauntlet of clinical studies with human participants, it could potentially lead to a groundbreaking new treatment for humans suffering from the deadly disease.

Silhouette of cannabis leaf

Maryland Gov. Wes Moore set to issue 175,000 pardons for marijuana convictions

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During a news conference, Moore said the executive order will affect “tens of thousands of Marylanders” convicted of misdemeanors. Some may have had more than one conviction pardoned through the process. Advocates praised the move as a way of removing barriers to housing, employment, or educational opportunities based on convictions for conduct that is no longer illegal.