Technology & innovation

This archive covers technology and innovation breakthroughs that improve lives, protect the environment, and expand human possibility. From medical devices to clean energy tools, the stories here focus on what’s working and who’s making it happen.

Model of a heart, for article on muvalaplin Lp(a) cholesterol

World-first drug lowers genetic form of “bad cholesterol” by up to 65%

Muvalaplin, a new pill from researchers at Monash University, lowered a dangerous genetic form of cholesterol by up to 65% in just two weeks during early trials. The drug targets lipoprotein(a), or Lp(a), a stickier cousin of LDL cholesterol that’s been called a “silent killer” because diet, exercise, and statins can’t touch it. Roughly one in five people worldwide carry elevated Lp(a), inherited risk they’ve long been told there’s nothing to do about. That muvalaplin works as a simple oral tablet, not an injection, could make it widely accessible if larger trials succeed. For global heart health, it’s a hopeful sign that even risks written into our DNA may not be the final word.