Public health & disease

Tbilisi, Georgia

Georgia certified malaria-free

The country of Georgia has been certified malaria-free following a nearly century-long fight to combat the disease, the World Health Organization has announced. It joins 45 countries that have achieved this milestone. Malaria has plagued Georgia since ancient times. During the post-war period, Georgia launched an intensive program focused on eliminating malaria. The campaign successfully interrupted the transmission of many strains by 1970 and the country remained malaria-free for 25 years. But by 2002 the disease had reemerged.

Landfill. A lot of plastic garbage. Environmental problems.

Thailand bans imports of plastic waste to curb toxic pollution

A law banning imports of plastic waste came into force in Thailand, after years of campaigning by activists. Thailand is one of several south-east Asian countries that has historically been paid to receive plastic waste from developed nations. Thai customs officials said more than 1.1 million tons of plastic scraps were imported between 2018 and 2021. Imports of plastic were often mismanaged, with many factories burning the waste rather than recycling it, leading to damage to human health and the environment.

Facility releasing air pollution|google

China has reduced sulphur dioxide emissions by more than two-thirds in the last 15 years

China has dramatically reduced local air pollution levels — particularly in its biggest cities — in the last decade. One rapidly declining pollutant is sulphur dioxide (SO2), which generates smog, causes ecologically-damaging acid rain, and is associated with higher rates of lung cancer and other respiratory issues. China has been able to make remarkable gains in curbing S02 emissions by putting emissions limits on coal plants and introducing desulphurization technologies that remove SO2 from smokestacks.

Depiction of intestines

“100% successful” cancer drug gets landmark U.S. FDA approval

Hugely promising cancer drug dostarlimab is one step closer to being widely available, after the U.S. Food and Drug Administration granted it Breakthrough Therapy Designation status. The drug, a programmed death receptor-1-blocking antibody, completely eradicated rectal cancer tumors without the need for surgery, radiation treatment, or chemotherapy. “Everyone on the clinical trial is doing great,” Memorial Sloan Kettering Cancer Center gastrointestinal oncologist Andrea Cercek said. “So far, 42 people have completed treatment, and all of them have no evidence of disease. Side effects were quite mild and well tolerated.”

A medical researcher in a laboratory examining vials for an article about mRNA lung cancer vaccine

Injection beats steroids for asthma and COPD attacks in first major advance in 50 years

Asthma and COPD treatment may be on the verge of its biggest advance in 50 years, after a clinical trial found that a single injection of benralizumab outperformed standard steroid tablets for treating acute attacks. The study, published in Lancet Respiratory Medicine, showed four times fewer treatment failures at three months and 30% fewer follow-up interventions among patients receiving the injection. The trial targeted eosinophilic flare-ups, the biological subtype behind roughly half of all asthma attacks and nearly a third of COPD episodes. Together, the two conditions kill an estimated 3.8 million people annually, yet the standard of care has remained largely unchanged since the 1970s.

Ovarian and Cervical Cancer Awareness. a Teal Ribbon

Cervical cancer deaths are plummeting among young U.S. women

Every year, thousands of American women die of cervical cancer. However, from 1992 to 2015, the number of deaths due to cervical cancer among U.S. women under the age of 25 fell steadily from each three-year period to the next, dropping roughly 75% altogether over that span. The sharp decline in cervical cancer deaths is likely due, at least in part, to the widespread introduction of the HPV vaccine in 2006.

Breakthrough genomic test identifies virtually any infection in one go

Researchers at University of California San Francisco (UCSF) have developed a single genomic test that can quickly detect virtually any kind of pathogen in a patient. This allows for much quicker diagnoses, enables targeted treatment to begin sooner, and could lower healthcare costs. Over the course of 7 years, researchers led by UCSF professor Charles Chiu tested 4,828 patients’ samples with its clinical mNGS method. The mNGS test accurately identified 86% of neurological infections.

digitally colorized scanning electron microscopic (SEM) image, depicts a blue-colored, human white blood cell, (WBC) known specifically as a neutrophil, interacting with two pink-colored, rod shaped, multidrug-resistant (MDR), Klebsiella pneumoniae bacteria

Global child deaths from pneumonia have been cut in half since 2009

Pneumonia kills 2,000 children under five worldwide every day, making it the world’s biggest infectious cause of death in children. The introduction of pneumococcal conjugate vaccines (PCVs) has significantly lowered the burden of death and disease from pneumonia, but millions of children remain unvaccinated. Since the public-private global health partnership Gavi supported the first roll-out of the PCV vaccine in 2009, 438 million children of all ages have been vaccinated in 64 countries, averting an estimated total of 1.2 million deaths by the end of 2023.

Close-up of a human eye with clear cornea, for an article about stem-cell cornea transplant research in Japan

Japanese researchers restore sight with stem-cell cornea transplants in a world first

Stem-cell cornea transplants have been successfully performed on human patients for the first time, with Japanese surgeons using reprogrammed induced pluripotent stem cells to restore vision in three of four participants — results that held for more than a year. Published in The Lancet in 2024, the trial offers a potential path around the global shortage of donor corneal tissue, which currently leaves millions without treatment options. Corneal disease is among the leading causes of blindness worldwide, making a scalable alternative to donor transplants significant. While the trial was small, a 75% sustained success rate in a first-in-human study is a meaningful early result.

A doctor is about to vaccinate a child

Sudan launches first malaria vaccine in landmark child health initiative

Malaria remains a leading cause of childhood mortality in Sudan, which has one of the highest malaria rates in the region. The disease claimed an estimated 7,900 lives in Sudan in 2023, though the actual toll may be higher due to ongoing conflict between rival militaries. The launch follows the arrival of the first consignment of 186,000 doses to Sudan in October and the campaign will begin across 15 health facilities in Gedaref and the Blue Nile states, benefitting more than 148,000 children under 12 months-old. In 2025 and 2026, the vaccine will be introduced in a further 129 localities.