Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

Viruses up close

Scientists eliminate HIV in animal genome in historic first

Existing HIV treatment used antiretroviral therapy, which is not a cure for HIV and requires lifelong use. In this study, researchers used a gene editing system to remove large fragments of HIV DNA from infected cells, along with a new drug regimen called long-acting slow-effective release. This approach eliminated HIV DNA from about one-third of the mice, marking the first time that HIV had been eradicated from the genomes of living animals.