Public health & disease

From disease eradication efforts to advances in vaccination and maternal health, this archive tracks real progress in public health. Stories here focus on what’s working — policies, interventions, and research that are improving and extending lives around the world.

Mosquito, for article on malaria parasite

Malaria breakthrough as scientists find ‘highly effective’ way to kill parasite

Malaria research has taken a genuinely hopeful turn, with Kenyan scientists at KEMRI identifying a bacterial derivative that kills Plasmodium falciparum through a mechanism the parasite hasn’t yet learned to resist — a critical advantage as drug resistance spreads. Building on earlier trials showing ivermectin-treated patients had blood lethal to mosquitoes, this research opens a new line of attack, originated by African scientists and designed around pregnant women and children from the start. Human trials still lie ahead, and that path is long — but the science points toward tools the world urgently needs.

|matthew t rader Y MzYPOLkXI unsplash, for article on overdose deaths

Overdose deaths in the United States drop for first time in two decades

Overdose deaths in the United States finally reversed course in 2018, ending nearly two decades of almost unbroken annual increases — a sign that the coordinated public health response is starting to work. Expanded naloxone access, medication-assisted treatment, and community outreach all appear to have contributed, though no single intervention gets the credit. The picture inside the data is mixed: while opioid deaths fell, deaths involving cocaine and methamphetamine rose, suggesting the epidemic shifted rather than ended. Still, experts say this is evidence that scaling up treatment saves lives — and that doing so remains the central, unfinished challenge.

Viruses up close

Scientists eliminate HIV in animal genome in historic first

Existing HIV treatment used antiretroviral therapy, which is not a cure for HIV and requires lifelong use. In this study, researchers used a gene editing system to remove large fragments of HIV DNA from infected cells, along with a new drug regimen called long-acting slow-effective release. This approach eliminated HIV DNA from about one-third of the mice, marking the first time that HIV had been eradicated from the genomes of living animals.