North & Central America

This archive covers progress stories from North and Central America, spanning the U.S., Canada, Mexico, and the nations of Central America. Readers will find reporting on health, environment, community resilience, and policy advances across the region.

Medical researcher in a lab examining vials related to asthma and COPD treatment and mRNA vaccine development, for article on benralizumab injection, for article on mRNA lung cancer vaccine

World’s first mRNA lung cancer vaccine enters human trials in seven countries

A landmark mRNA lung cancer vaccine is now being tested in human patients for the first time, marking a historic milestone in cancer treatment. BNT116, developed by BioNTech, uses the same messenger RNA technology behind COVID-19 vaccines to train the immune system to recognize and destroy non-small cell lung cancer cells. The phase 1 trial spans 34 sites across seven countries, with roughly 130 patients enrolled. Unlike chemotherapy, this approach targets only tumor cells, potentially offering a more precise and lasting defense against the world’s deadliest cancer, which kills 1.8 million people annually.

Medications, for article on Medicare drug price negotiation

The U.S. negotiates Medicare drug price cuts that will save billions for U.S. citizens

Medicare drug price negotiation just delivered its first results, and the projected savings land at roughly $6 billion a year once new prices take effect in January 2026. After nearly six decades of being legally barred from bargaining with drugmakers, Medicare negotiated discounts on 10 widely used medications, including the blood thinner Eliquis and the diabetes drug Januvia. Some prices dropped by as much as 79%, with the deepest cuts going to drugs that faced the least competition. Around 9 million enrollees use these medications, and a new $2,000 annual cap on out-of-pocket drug costs adds further relief. Beyond the dollars, this shifts what’s politically possible — moving the U.S. closer to how most wealthy democracies have long approached medicine pricing.

Charging an EV, for article on municipal fleet electrification, for article on tailpipe emission standards

Major new commitment from nearly 350 mayors to accelerate U.S. electric vehicle transition

Nearly 350 U.S. mayors just pledged to electrify at least half their city vehicle fleets by 2030, from police cruisers to garbage trucks to buses. They’re also committing to grow public EV charging fivefold by 2035, with 40% of those new chargers going to neighborhoods that have long breathed the dirtiest air. The bipartisan Climate Mayors network behind the pledge has grown from three founders a decade ago to more than 750 mayors representing close to 60 million Americans. When cities buy electric at this scale, they don’t just clean up local streets — they send a signal that reshapes what manufacturers build, proving that climate progress can move forward city by city, even when Washington stalls.

Kim Coco Iwamoto, for article on Hawaii transgender lawmaker

Kim Coco Iwamoto to become Hawaii’s first trans lawmaker

Hawaii just elected its first transgender state lawmaker, and she did it by unseating the sitting House Speaker. Kim Coco Iwamoto won her Honolulu Democratic primary with 49.3% of the vote, edging out Scott Saiki by about five percentage points without the backing of the party establishment. A longtime civil rights attorney and former Board of Education member, Iwamoto ran on a platform that includes the Green New Deal, affordable housing, and stronger protections for LGBTQ+ youth in foster care. At a moment when transgender Americans are facing a wave of legislative attacks, a win like this — built on years of organizing and persistence — offers a hopeful reminder of what representation can still look like.

Shot of a young male doctor standing with his arms crossed in an office at a hospital, for article on HBCU medical school funding

Michael Bloomberg gives $600 million to four Black medical schools’ endowments

HBCU medical schools just received $600 million from Bloomberg Philanthropies, with Howard, Meharry, and Morehouse each getting $175 million and Charles R. Drew receiving $75 million. The gift will more than double the endowments at three of the four schools, giving them the kind of long-term, flexible funding that lets institutions plan decades ahead — recruiting faculty, expanding class sizes, and offering scholarships without leaning so hard on tuition. An additional $5 million supports a new medical school launching at Xavier University of Louisiana with Ochsner Health. Black Americans make up roughly 13% of the U.S. population but less than 6% of practicing physicians, and research consistently links Black doctors to better outcomes for Black patients. Training more of them is one of the clearest paths toward closing that gap.

Good news for LGBTQ rights, for article on Thailand marriage equality, for article on conversion therapy ban, for article on same-sex partnership rights, for article on forced outing of queer students, for article on Greece same-sex marriage

California passes first-in-the-nation law banning forced outings of queer students in state public schools

California just became the first state in the country to ban schools from forcibly outing queer students, after Governor Newsom signed the SAFETY Act into law and it took effect immediately. The bill, which passed the State Assembly 60-15, also shields teachers from retaliation if they refuse to disclose a student’s gender identity to parents without consent. It arrived after years of organizing by educators like Karen Poznanski, a Murrieta teacher and parent of a nonbinary child, whose complaint helped trigger a state investigation. Eight other states currently require this kind of outing, so California’s move offers a real counter-model. For queer kids deciding when and how to come out, this puts one of life’s most tender conversations back in their own hands.

Fervo Energy geothermal plant, for article on enhanced geothermal power purchase agreement

World’s biggest geothermal power purchase agreement completed in western U.S.

A Utah geothermal project just secured what developers are calling the world’s largest geothermal power purchase agreement — a 15-year deal to deliver 320 megawatts of always-on clean electricity to Southern California Edison, enough to power roughly 350,000 homes. Fervo Energy’s Cape Station plant uses horizontal drilling borrowed from the oil and gas industry to circulate water through deep hot rock, unlocking geothermal power in places where it was never viable before. First electrons are expected to flow in 2026, with the rest coming online by 2028. For a clean grid that needs to run when the sun sets and the wind stops, this kind of steady, weather-proof power may be the missing piece — and a signal that geothermal is ready for prime time.

Good news for public health, for article on CAB-LA HIV prevention, for article on lenacapavir HIV prevention, for article on HIV infections in young men

New twice-yearly shot to prevent HIV achieves 100% success rate in late-stage trial

Lenacapavir, a twice-yearly HIV prevention shot, protected every single one of 2,134 women who received it in a late-stage trial across South Africa and Uganda — a 100% efficacy result so striking that monitors ended the blinded phase early. The breakthrough matters because daily prevention pills, while powerful in theory, often falter in real life: stigma, forgotten doses, and disrupted routines all chip away at protection. Two clinic visits a year, by contrast, means a full year of coverage. The remaining hurdle is access, with advocates pressing manufacturer Gilead to license generic versions for the regions hardest hit. If that happens, a tool this effective could reshape the global push to end the HIV epidemic by 2030.

Close up of a Black-faced impala., for article on white-eared kob migration

South Sudan launches epic effort to protect the world’s largest mammal migration

South Sudan’s great migration — now confirmed as the largest land mammal movement on Earth — sweeps up to six million animals across the floodplains each year, following rainfall in a vast circular loop. A new 10-year partnership between the South Sudanese government and the nonprofit African Parks is working to keep it that way, blending aerial surveys and GPS collars with generations of Indigenous knowledge. Seventeen ethnic groups share this landscape, and for centuries they’ve left informal corridors of “No Man’s Land” open so wildlife can pass freely between them. Tribal members now serve as observers, technicians, and field operators in the conservation effort itself. It’s a hopeful reminder that the most enduring protection often grows from the people who’ve always lived alongside what they’re protecting.

Silhouette of cannabis leaf, for article on Maryland marijuana pardons

Maryland Gov. Wes Moore set to issue 175,000 pardons for marijuana convictions

Maryland’s marijuana pardons just cleared more than 175,000 convictions in a single executive order — the largest state-level pardon any governor has ever signed. Governor Wes Moore framed it as unfinished business from legalization itself, noting that people arrested for cannabis decades ago still carry those records into job interviews, housing applications, and college admissions today. The order falls hardest in favor of Black Marylanders, who were arrested for cannabis at three times the rate of white residents before the state legalized recreational use in 2023. Moore was honest about the limits: a pardon can’t return lost years. But paired with the federal push to reschedule marijuana, it signals a country slowly reckoning with who paid the price of the war on drugs.