Technology & innovation

This archive covers technology and innovation breakthroughs that improve lives, protect the environment, and expand human possibility. From medical devices to clean energy tools, the stories here focus on what’s working and who’s making it happen.

Sick woman

U.K. researchers identify and treat major cause of inflammatory bowel disease

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For the first time, a major trigger in inflammatory bowel disease (IBD) and related conditions has been identified, and existing drugs can stamp it out, in what scientists call a “massive step” in successfully treating these debilitating chronic conditions. Researchers at the Francis Crick Institute, in collaboration with University College London (UCL) and Imperial College London (ICL), have uncovered a problem gene enhancer that stimulates action along a specific biological pathway that causes IBD inflammation.

X-ray image of the intestine

New bowel cancer drug is found to be 100% effective

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An immunotherapy drug could spare bowel cancer patients the need for surgery and chemotherapy after results showed it was effective in 100% of cases. Jemperli from British pharmaceutical company GSK showed “unprecedented results”, the firm said, with no evidence of disease in all patients treated. The data showed all 42 patients in a trial led by Memorial Sloan Kettering Cancer Center in the U.S. had a complete response to treatment, with no evidence of tumors on scans.

Holding breast cancer ribbon, for article on breast cancer recurrence blood test

New blood test can predict breast cancer return

By / / Good News For Humankind

A new blood test for breast cancer recurrence spotted returning disease an average of 15 months before symptoms or scans — and in one case, a full 41 months ahead of diagnosis. In a UK trial of 78 patients, the test correctly flagged every woman who later relapsed, scanning for 1,800 cancer-related mutations in tiny fragments of tumour DNA left circulating after treatment. Lead researcher Dr. Isaac Garcia-Murillas explained that dormant cells too few to show up on scans can trigger relapse years later — exactly the blind spot this test targets. If larger studies confirm the results, a simple blood draw could give oncologists precious extra time to act, reshaping how recurrence is caught worldwide.

Car HUD

Chinese scientists discover way to make batteries more efficient

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A new water-based battery design is safer and more energy-efficient than traditional lithium-ion batteries, researchers from the Chinese Academy of Sciences claim. Today’s lithium batteries have enabled the rise of EVs, but their flammable organic electrolytes make them a fire risk, and their energy density puts a cap on EV driving range. The new water-based design replaces those combustible components with a safer, more stable water-based electrolyte that can pack way more energy into the same space.

A researcher handling a vaccine vial in a clinical lab for an article about cancer vaccine trials, for article on cancer chemotherapy, for article on personalized cancer vaccine

NHS launches world-first cancer vaccine matchmaking program in England

By / / Good News For Humankind

Cancer vaccine trials are now being fast-tracked through a landmark NHS program in England that matches patients with personalized mRNA vaccines built around their individual tumors. The Cancer Vaccine Launch Pad, operating across 30 hospitals, uses the same mRNA technology behind COVID-19 vaccines to design custom treatments targeting each patient’s unique cancer mutations. The program aims to eliminate remaining cancer cells after surgery before they can return. Early immune response data is encouraging, and a 2024 trial showed a 44% reduction in melanoma recurrence when similar vaccines were combined with immunotherapy.

Cryo sauna for whole body cryotherapy

Cryo-cooling breakthrough slashes the energy cost of serious cold by 71%

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Cryogenic cooling is used to preserve tissues, eggs, sperm, and embryos and CAT scanners, CERN’s massive particle accelerators, and the James Webb Space Telescope possible. It may also one day be the key to making fusion power or quantum computers a reality. However, it is also quite energy-intensive. Fortunately, researchers at the U.S.’s National Institute of Standards & Technology have recently discovered a way to reach near-absolute zero up to 3.5 times faster or using about 71% less energy.

Wooden satellite, for article on wooden satellite

Japanese scientists build world’s first wooden satellite

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The satellite dubbed LignoSat, a collaboration between Kyoto University and the company Sumitomo Forestry, is reportedly slated for launch in September onboard a SpaceX rocket. If successful, the tiny device — just four inches on each side — could represent a major breakthrough in space sustainability efforts. The idea is that it’ll burn up entirely upon reentry, vastly reducing its environmental impact compared to traditional metal spacecraft.

A neuron or nerve cell is an electrically excitable cell, for article on ALS synapse-regenerating pill

Breakthrough synapse-regenerating ALS pill moves to phase 2 human trials

By / / Good News For Humankind

A once-daily ALS pill designed to rebuild neural connections — not just slow their loss — has cleared FDA approval to begin Phase 2 trials, with patients across the U.S. starting doses in April 2024. SPG302 works on synapses, the tiny junctions where neurons talk to each other, which start vanishing before motor neurons themselves die. Every ALS drug currently on the market aims to slow decline; this one is being tested for whether it can actually help recover lost function. For the roughly 30,000 Americans living with ALS, that’s a genuinely different question to be asking. If it works, it could reshape how researchers approach neurodegenerative disease far beyond ALS.

Cargo ship at sunset

New piloting approach cuts cargo ship emissions by 17.3% in first trials

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Currently, most cargo ships go as quickly as they can from port A to port B. When they get there, they sit still and wait at idle, continuing to burn fuel, until it’s time for them to dock. The Blue Visby Solution simply tells the ships to slow down, so they arrive at port right on time. Pushing all that bulk through the water at a slower speed cuts down hugely on hydrodynamic drag, so the engines burn considerably less fuel.

Ambulance and EMT workers at night

Researchers develop a ‘game-changing’ blood test for stroke detection in the field

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Stroke is the top cause of disability worldwide—and the second leading cause of death—but early intervention can prevent severe consequences, and a new tool could be a game-changer. Researchers at Massachusetts’ Brigham and Women’s Hospital developed a new test by combining blood-based biomarkers with a clinical score to identify patients experiencing large vessel occlusion strokes (LVO) with high accuracy.