Technology & innovation

This archive covers technology and innovation breakthroughs that improve lives, protect the environment, and expand human possibility. From medical devices to clean energy tools, the stories here focus on what’s working and who’s making it happen.

Ghanaian child carrying load on head, for article on R21 malaria vaccine

Ghana first country to approve ‘world-changer’ malaria vaccine

Ghana’s approval of the R21 malaria vaccine — the first anywhere in the world — clears the way for children as young as five months to be protected against a disease that kills roughly 620,000 people every year, mostly young kids in Africa. Developed at Oxford’s Jenner Institute, R21 showed up to 80% effectiveness in early trials and is expected to cost just a couple of dollars per dose. The Serum Institute of India is preparing to produce up to 200 million doses a year, with a factory rising in Accra so supply stays close to home. After a century of scientific near-misses, an African regulator stepped forward and said: this one is ready.

Scientist examines the result of a plaque assay, for article on gene therapy cure MLD

Researchers cure toddler of deadly metachromatic leukodystrophy (MLD) for first time in history

Gene therapy has cured 19-month-old Teddi Shaw of metachromatic leukodystrophy, making her the first NHS patient treated for this rare, fatal nervous system disease. After a single infusion of Libmeldy at Royal Manchester Children’s Hospital, she’s now running around, chattering away, and showing no signs of the illness that typically kills children before age eight. The treatment works by correcting a faulty gene in the child’s own stem cells, eliminating the disease at its root rather than managing it. Her family’s joy is tempered by grief — Teddi’s older sister was diagnosed too late for the therapy to help, fueling calls for newborn screening. It’s a glimpse of medicine’s next era: one-time cures for inherited conditions, if access and early detection can keep pace.