Public health & disease

Indian flag

India eliminates trachoma as a public health problem

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The World Health Organization has validated the world’s most populous country as having eliminated trachoma as a public health problem. India joins Nepal and Myanmar in the WHO South-East Asia Region and 19 other countries globally that have previously achieved this feat. Though trachoma is preventable, blindness from trachoma is extremely difficult to reverse. Trachoma continues to be a public health problem in 39 countries and is responsible for the blindness of about 1.9 million people.

Metal pipes

U.S. announces 10-year deadline to remove all lead pipes nationwide

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President Biden has announced $2.6 billion in funding to replace all lead pipes in the United States as part of a new EPA rule that will require lead pipes to be identified and replaced within 10 years using the new funding from the Bipartisan Infrastructure Act. The EPA estimates that nine million homes in the U.S. still have lead pipes. “Studies show … communities of color have been the hardest hit,” Mr. Biden said. “One study showed Black children were at least two times more likely to have elevated levels of lead in their blood than children of other racial groups. We have an obligation to make things right.”

Pollution from industrial facility

Study finds mercury pollution from human activities is declining

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In a new study from the Massachusetts Institute of Technology, researchers analyzed measurements from all available monitoring stations in the Northern Hemisphere and found that atmospheric concentrations of mercury declined by about 10% between 2005 and 2020. They used two separate modeling methods to determine what is driving that trend. Both techniques pointed to a decline in mercury emissions from human activity as the most likely cause.

Virus up close

‘Gamechanger’ HIV prevention drug to be made available cheaply in 120 countries

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Gilead Sciences says it has signed agreements with six manufacturers to make and sell generic lenacapavir in 120 “high-incidence, resource-limited” countries. Lenacapavir, given as a twice-yearly injection, has shown strong results for HIV prevention. It stopped infection in a trial involving girls and women in South Africa and Uganda, and offered almost complete protection in a second trial that mainly involved men across Argentina, Brazil, Mexico, Peru, South Africa, Thailand, and the U.S.

World Health Organization approves first mpox diagnostic test for emergency use

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Mpox, previously known as monkeypox, is an infectious disease caused by the monkeypox virus. A global outbreak first emerged in May 2022 which WHO said constituted a public health emergency of international concern – the highest level of alarm under international health law. Africa has seen an unprecedented increase and expansion in mpox cases this year, with transmission mainly centered in the Democratic Republic of the Congo. WHO said early diagnosis is critical as it enables timely treatment and care, as well as control of the virus. A new test from Abbott Molecular now makes that much more possible.

Scientists in the U.K. developing world’s first vaccine to prevent ovarian cancer

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Researchers at the University of Oxford are working on the world’s first ovarian cancer vaccine, aiming to prevent the disease that kills nearly 26,000 women in the European Union every year. The vaccine, called OvarianVax, would train the immune system to recognize and fight back against the earliest stages of ovarian cancer, one of the most common forms of cancer among women which often isn’t detected until a later stage when it’s harder to treat. Cancer Research U.K. will fund the OvarianVax research with up to £600,000 for the effort.

Good news for scientific research

University of Toronto researchers develop method to accelerate forensic analysis in sexual assault cases

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The entire process currently can take days, weeks, or longer. To speed things up, the researchers focused on the first step: separating two individuals’ DNA from a single sample. At present, this is usually done manually by trained and experienced experts. The new method uses a process called ’differential digestion” using digital microfluidics that helped simplify the overall process and reduce the number of manual steps needed to isolate the assailant’s DNA from 13 to five.

Depiction of embryonic stem cells in amniotic fluid

In world first, stem cells reverse woman’s diabetes

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In the first trial of its kind, Deng Hongkui, a cell biologist at Peking University in Beijing, and his colleagues extracted cells from three people with type 1 diabetes and reverted them into a pluripotent state, from which they could be molded into any cell type in the body. Now, a 25-year-old woman with type 1 diabetes started producing her own insulin less than three months after receiving a transplant of reprogrammed stem cells. She is the first person with the disease to be treated using cells that were extracted from her own body.

Neurons inside human brain

Synapse-restoring pill set for human trials as novel schizophrenia treatment

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Spinogenix is the American company behind the once-a-day pill that restored lost nerve cell connections in people with amyotrophic lateral sclerosis (ALS). Having been granted approval from the Australia Human Research Ethics Committee (HREC), it is now actively enrolling participants for its Phase 2 clinical trial to evaluate the safety, effectiveness, tolerability, and pharmacodynamics of once-a-day SPG302 as a treatment for schizophrenia.

Closeup hands of old woman suffering from leprosy

Jordan becomes first country to receive WHO verification for eliminating leprosy

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Jordan has not reported any autochthonous cases of leprosy for over two decades, a testament to its strong political commitment and effective public health strategies to eliminate the disease. Following up on the Ministry of Health’s interest in verifying the elimination of leprosy, the World Health Organization (WHO) commissioned an independent team to assess this situation. After an extensive review, the verification team recommended that WHO acknowledges leprosy has been eliminated in Jordan.

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