Danish scientists design new form of insulin that automatically switches itself on and off

Smart insulin that reads blood sugar in real time and adjusts its own activity has cleared a major hurdle in animal trials, according to Danish researchers publishing in Nature. The molecule switches on when glucose climbs and powers down as levels normalize, mimicking the feedback loop of a healthy pancreas. That matters because conventional insulin can overshoot and trigger dangerously low blood sugar, a side effect that endangers people living with diabetes every day. Scientists have chased this idea for more than 40 years, and earlier candidates kept stumbling in living bodies. For the more than 500 million people worldwide managing diabetes, an insulin that doses itself would be a quiet revolution — bringing daily care closer to how the body was meant to work.