Chinese scientists develop novel gene therapy that allows deaf children to hear for the first time
Gene therapy has restored partial hearing in four out of five deaf children in a Shanghai trial, with each child regaining roughly 60 to 65 percent of typical hearing ability. The Fudan University team used a harmless virus to ferry a working copy of the otoferlin gene directly into the inner ear, where it began producing the protein these children had been missing since birth. Most had heard little or nothing their whole lives, so even partial hearing opens a window for spoken language to develop during early childhood. Parallel trials at Cambridge and Regeneron suggest the field is converging on a shared approach — a hopeful proof of concept that could one day extend to many more forms of inherited deafness.
