Many available pain medications aren’t effective in reducing this often-debilitating type of chronic pain. However, researchers at the University of Texas at Austin (UT Austin), in collaboration with UT Dallas and the University of Miami, may have advanced the treatment of neuropathic pain by discovering a molecule that reduces mechanical hypersensitivity in mice.
Hereditary angioedema, or HAE, is a rare disease that affects about one in 50,000 people. It is caused by a genetic mutation that leaves patients with leaky blood vessels, causing erratic bouts of swelling. Dr. Hilary Longhurst, the principal investigator at New Zealand’s Te Toka Tumai, Auckland City hospital, said the new single-dose therapy appeared to provide a permanent cure for her patients’ “very disabling symptoms”.
A recent trial of 786 people – conducted by Dr. Nicholas Ashton at the University of Gothenburg in Sweden and colleagues – found the new test to be as accurate at detecting the signs of Alzheimer’s as painful lumbar punctures, and better than a range of other tests currently being worked on. Experts say it could pave the way for national screening programs for people 50 and over, and that current treatments could work better with the cases picked up earlier.
The vaccine- developed by Dr. Thomas Wagner of U.S.-based Orbis Health Solutions – has already been tested in hundreds of patients with advanced forms of melanoma in Phase 2 clinical trials. The most recent data showed nearly 95% of people given only the vaccine were still alive three years after starting treatment and 64% were still disease-free. Among the most advanced forms of melanoma, disease-free survival after three years for people with stage III disease was 60% in the vaccine-only group, compared to about 39% in the placebo group.
A landmark test of beaming solar power to Earth from a satellite has concluded successfully after a year-long mission. Led by scientists at the California Institute of Technology, the mission completed all three of its primary experiments to test key technology for such an endeavor. They included a new origami-inspired solar panel structure, different cell designs, and a microwave transmitter.
Between 1980 and 2022, consumption poverty fell from 33.8% to 6.0% even though the official poverty rate indicated a drop by only 1.5 percentage points over that same period. According to researchers from the University of Notre Dame, consumption, which measures what families are able to purchase in terms of food, housing, transportation, and other goods and services, offers a better indicator of economic well-being than income, which can fluctuate for reasons unrelated to well-being.
Researchers at Duke-NUS Medical School in Singapore have developed an intranasal COVID-19 vaccine that enhances the immune system’s response to the virus, providing longer-lasting, greater protection than vaccine injections, even against new and emerging variants. The novel vaccine candidate could mean fewer boosters in future.
The team from U.S. biotech firm Novelna wrote: “At stage I (the earliest cancer stage) and at the specificity of 99%, our panels were able to identify 93% of cancers among males and 84% of cancers among females.” It believes its cheaper, less invasive multi-cancer screening test could be a ‘gamechanger.’
Biotech researchers at the Chinese Academy of Sciences (CAS) say the new method could feed livestock much more efficiently than natural plants, while using a1/1000th as much land as farming.
The U.S. Department of Energy has announced that four additional heat pump manufacturers successfully produced heat pump prototypes as part of the Residential Cold Climate Heat Pump (CCHP) Technology Challenge. Launched in 2021, this initiative brings together public and private sector stakeholders to address technical challenges and market barriers to adopting next-generation cold-climate heat pumps—a key clean energy technology that can potentially save households $500 a year or more on their utility bills while also slashing harmful carbon emissions.
