U.S. scientists restore a last-resort antibiotic’s power over superbugs
Drug-resistant infections already kill more than a million people a year worldwide and contribute to nearly 5 million deaths — a toll projected to climb toward 10 million annually by 2050 if nothing changes. Now researchers at Cold Spring Harbor Laboratory in New York and Scripps Research and in California have found a way to fight back without inventing new drugs: a small companion molecule, pghi-4, that disables a key bacterial defense and lets vancomycin kill resistant bacteria again in lab tests. The approach is years from clinical use, but restoring the antibiotics medicine already has could eventually save millions of lives.









