Public health & disease

Brain scan

Belgian boy becomes first child in the world to be cured of brain stem glioma

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Brain stem glioma, officially called diffuse intrinsic pontine glioma (DIPG), is rare and lethal, diagnosed in just 300 children annually in the United States. The two-year survival rate is 10%, and no drug is widely available for its treatment beyond radiotherapy. After the boy’s diagnosis, the family traveled to France to take part in a randomized controlled trial. He was randomly assigned the drug everolimus, which he took for more than 5 years with remarkable success.

Dentist's Hand Taking Saliva Test From Woman's Mouth

Hand-held test for breast cancer uses your saliva and gives accurate readings in 5 seconds

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A new hand-held portable device is not only extremely quick and easy to use but very cost effective, say scientists from the University of Florida and National Yang Ming Chiao Tung University in Taiwan. Compared to the costly alternatives of Mammograms, which expose women to radiation—or MRIs and ultrasounds which require expensive equipment—researchers called the device revolutionary.

Colorful ribbons on pink background|Doctor

New drug offers breakthrough in treatment of asbestos-linked cancer

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Scientists at Queen Mary University of London have developed a drug to treat mesothelioma, a notoriously deadly and hard-to-treat cancer linked to asbestos, in the biggest breakthrough in two decades.
An international trial spanning five countries found that the new drug, ADI-PEG20, cuts off the tumor’s food supply and quadruples three-year survival rates. It is the first of its kind to be successfully combined with chemotherapy in 20 years.

Assortment of pills

Novel AI model rapidly determines if an antidepressant will work

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Amsterdam University Medical Center (UMC) and Radboud UMC researchers have developed an algorithm that, based on patient MRI scans and other data, can determine within a week if a particular antidepressant will, offering faster relief and minimizing often painful and damaging side effects. “This is important news for patients,” said Liesbeth Reneman, Professor of Neuroradiology at Amsterdam UMC. “Normally, it takes six to eight weeks before it is known whether an antidepressant will work.”

Depiction of nerve cells

Researchers discover an effective non-opioid treatment for nerve pain

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Many available pain medications aren’t effective in reducing this often-debilitating type of chronic pain. However, researchers at the University of Texas at Austin (UT Austin), in collaboration with UT Dallas and the University of Miami, may have advanced the treatment of neuropathic pain by discovering a molecule that reduces mechanical hypersensitivity in mice.

Empty office desk and chairs

Germany launches large four-day workweek trial

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In February, 45 companies and organizations in Europe’s largest economy will introduce a 4-day workweek for half a year. Employees will continue to receive their full salary. Advocates argue that a 4-day workweek would increase worker productivity and, by consequence, help alleviate the country’s skilled labor shortage.

Chromosomes

Gene therapy hailed as ‘medical magic wand’ for hereditary swelling disorder

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Hereditary angioedema, or HAE, is a rare disease that affects about one in 50,000 people. It is caused by a genetic mutation that leaves patients with leaky blood vessels, causing erratic bouts of swelling. Dr. Hilary Longhurst, the principal investigator at New Zealand’s Te Toka Tumai, Auckland City hospital, said the new single-dose therapy appeared to provide a permanent cure for her patients’ “very disabling symptoms”.

Back of a school bus

Miami commits to putting 100 electric school buses on the road

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Miami-Dade county is set to receive nearly $20 million from the Environmental Protection Agency to help cover the costs of 50 new electric school buses and 16 DC fast chargers, bringing the public school district’s total to 100 electric buses. Miami-Dade county is one of four school districts selected to receive a total of $33,175,000 through the EPA’s first Clean School Bus Program’s Grants Competition.

Person having blood drawn

Breakthrough Alzheimer’s blood test could detect disease 15 years before symptoms emerge

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A recent trial of 786 people – conducted by Dr. Nicholas Ashton at the University of Gothenburg in Sweden and colleagues – found the new test to be as accurate at detecting the signs of Alzheimer’s as painful lumbar punctures, and better than a range of other tests currently being worked on. Experts say it could pave the way for national screening programs for people 50 and over, and that current treatments could work better with the cases picked up earlier.

Mosquito

Historic malaria vaccine rollout begins in Cameroon

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The rollout of the world’s first malaria vaccine has begun in Cameroon, which is said to usher in a “transformative chapter in Africa’s public health history”. The RTS,S vaccine – 662,000 doses of it – will be administered to children in the west African country, the first to be vaccinated after successful trials of the drug in Ghana, Kenya, and Malawi between 2019 and 2021.

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