Public health & disease

Image of brain

New mRNA cancer vaccine triggers fierce immune response to fight malignant brain tumor

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In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain tumor.

In a first-ever human clinical trial of adult patients, an mRNA cancer vaccine developed at the University of Florida reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain tumor. The results mirror those in 10 pet dog patients suffering from brain tumors, as well as results from preclinical mouse models. The breakthrough will now be tested in a Phase 1 pediatric clinical trial.

Vials of blood

Bacterial enzyme strips away blood types to create universal donor blood

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There’s a global shortage of blood supplies needed for life-saving transfusions due to factors that include an aging population with a higher demand for it and a lack of volunteer donors. To help address this challenge, researchers at the Technical University of Denmark (DTU) and Lund University, Sweden, have used enzymes produced by a common gut bacteria to remove the A and B antigens from red blood cells, bringing them one step closer to creating universal donor blood.

Mosquito on a leaf

New types of mosquito bed nets could cut malaria risk by up to half, trial finds

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Nets treated with two types of insecticide rather than one were trialed in 17 African countries where malaria is endemic between 2019 and 2022. During clinical trials when a net was coated with the insecticides pyriproxyfen or chlorfenapyr, alongside pyrethroid, malaria transmissions were reduced by between 20% and 50%. More than 600,000 people died from malaria in 2022 and 249 million people were infected, according to the latest data from the World Health Organization.

Person filling syringe with vaccine

Nigeria becomes world’s first country to introduce ‘revolutionary’ meningitis vaccine

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Nigeria has become the first country to roll out a “revolutionary” five-in-one vaccine against meningitis, the World Health Organization has announced. The Men5CV vaccine offers a powerful shield against the five major strains of the meningococcal bacteria that cause the disease. Known by the brand name MenFive, it provides broader protection than the vaccine currently used in much of Africa.

Water flowing from faucet

U.S. Environmental Protection Agency announces first-ever national regulations for “forever chemicals” in drinking water

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Commonly called “forever chemicals,” PFAS are synthetic chemicals found nearly everywhere — in air, water, and soil — and can take thousands of years to break down in the environment.

The EPA has stated there is no safe level of exposure to PFAS without risk of health impacts, but now it will require that public water utilities test for six different types of PFAS chemicals to reduce exposure in drinking water. The new standards will reduce PFAS exposure for 100 million people, according to the EPA, and prevent thousands of deaths and illnesses.

Elderly man

Thousands of people in the U.K. to receive landmark trials for dementia blood tests

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Thousands of people across the U.K. who are worried about their memory will receive blood tests for dementia in two trials that doctors hope will help to revolutionize the low diagnosis rate. Teams from the University of Oxford and University College London will lead the trials to research the use of cheap and simple tests to detect proteins for people with early stages of dementia or problems with cognition, with the hope of speeding up diagnosis and reaching more people.

Elderly person smiling

Global life expectancy increased by 6.2 years between 1990 and 2021

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A new study from the University of Washington’s Institute for Health Metrics and Evaluation found that the super-region of Southeast Asia, East Asia, and Oceania had the world’s largest net gain in life expectancy between 1990 and 2021 (8.3 years), largely due to reductions in mortality from chronic respiratory diseases, stroke, lower respiratory infections, and cancer.

Contraceptives

Canada to make contraception for women free

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The government will pay for the most widely used methods to avoid pregnancy, such as IUDs, contraceptive pills, hormonal implants or the day after pill, for the nine million Canadian women of reproductive age, Deputy Prime Minister Chrystia Freeland said at a press conference. “Women should be free to choose the contraceptives they need without cost getting in the way. So, we’re making contraceptives free,” Prime Minister Justin Trudeau said.

Hand holding living cannabis plant

Germany approves partial legalization of cannabis

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The new law will allow adults to carry up to 25 grams of cannabis for their own consumption and store up to 50 grams at home. Public consumption will be allowed, so long as it is not within sight of children or near sports facilities. It will also be prohibited in pedestrian zones between 7 a.m. and 8 p.m. It is slated to come into effect on April 1.

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