University of Southern California

A surgical team performing a complex organ procedure for an article about bladder transplant surgery, for article on bladder transplant

California surgeons perform the world’s first successful bladder transplant

Bladder transplant surgery has been successfully performed on a human patient for the first time in medical history. Oscar Larrainzar, a 41-year-old California father of four, received a donor bladder and kidney simultaneously in early May 2025, after cancer treatment left him without either organ. He has since been taken off dialysis entirely. The procedure was developed over four years by surgeons at USC and UCLA, who now plan a formal clinical trial to refine the technique. For patients who have lost bladder function, transplantation is no longer theoretical.