United Kingdom

Model lungs

Doctors hail first breakthrough in asthma and COPD treatment in 50 years

A trial from King’s College London found offering patients a new injection was more effective than the current care of steroid tablets, and cuts the need for further treatment by 30%. The results, published in the Lancet Respiratory Medicine journal, could be transformative for millions of people with asthma and COPD around the world. Lead investigator Professor Mona Bafadhel said: “This could be a gamechanger for people with asthma and COPD. Treatment for asthma and COPD exacerbations have not changed in 50 years, despite causing 3.8 million deaths worldwide a year combined.”

Ovarian and Cervical Cancer Awareness. a Teal Ribbon

New cervical cancer treatment regime ‘cuts risk of dying from disease by 40%’

Doctors are hailing a “remarkable” new treatment regime for cervical cancer developed by researchers at University College London that reduces the risk of dying by 40%, in the biggest advance against the disease in 25 years. The new treatment plan was tested in patients recruited over 10 years from the UK, Mexico, India, Italy, and Brazil. Cervical cancer is the fourth most common cancer in women globally, with about 660,000 new cases and 350,000 deaths every year, according to the World Health Organization.

Scientists in the U.K. developing world’s first vaccine to prevent ovarian cancer

Researchers at the University of Oxford are working on the world’s first ovarian cancer vaccine, aiming to prevent the disease that kills nearly 26,000 women in the European Union every year. The vaccine, called OvarianVax, would train the immune system to recognize and fight back against the earliest stages of ovarian cancer, one of the most common forms of cancer among women which often isn’t detected until a later stage when it’s harder to treat. Cancer Research U.K. will fund the OvarianVax research with up to £600,000 for the effort.

Model lungs

World-first lung cancer vaccine trials launched across seven countries

Lung cancer is the world’s leading cause of cancer death, accounting for about 1.8 million deaths every year. Now experts are testing a new jab that instructs the body to hunt down and kill cancer cells – then prevents them from ever coming back. Known as BNT116 and made by BioNTech, the vaccine is designed to treat non-small cell lung cancer, the most common form of the disease. The phase 1 clinical trial, the first human study of BNT116, has launched across 34 research sites in seven countries: the U.K., U.S., Germany, Hungary, Poland, Spain, and Turkey.

Big Ben with bridge over Thames and flag of England against blue sky in London

British voters elect record number of women to Parliament

After the recent elections, there will now be at least 242 female Members of Parliament in the new U.K. government. The previous record was set in 2019 when 220 women were elected to the House of Commons. Before that in 2017, it was 207 and 196 in 2015. New Prime Minister Keir Starmer’s cabinet will also have the highest number of female ministers in history, as Rachel Reeves became the first female chancellor ever.

Fervo Energy geothermal plant

World’s biggest geothermal power purchase agreement completed in western U.S.

It’s only been one year since Fervo Energy unveiled a novel concept in geothermal energy harvesting at its Project Red pilot plant in Nevada. Now the company has signed a 15-year agreement with Southern California Edison to provide 320 MW of power to the utility, which will power about 350,000 homes. The power will be provided by Fervo’s Cape Station project that is currently being built in southwest Utah, with the first 70 MW coming online in 2026 and the balance clicking on in 2028.

Sick woman

U.K. researchers identify and treat major cause of inflammatory bowel disease

For the first time, a major trigger in inflammatory bowel disease (IBD) and related conditions has been identified, and existing drugs can stamp it out, in what scientists call a “massive step” in successfully treating these debilitating chronic conditions. Researchers at the Francis Crick Institute, in collaboration with University College London (UCL) and Imperial College London (ICL), have uncovered a problem gene enhancer that stimulates action along a specific biological pathway that causes IBD inflammation.

X-ray image of the intestine

New bowel cancer drug is found to be 100% effective

An immunotherapy drug could spare bowel cancer patients the need for surgery and chemotherapy after results showed it was effective in 100% of cases. Jemperli from British pharmaceutical company GSK showed “unprecedented results”, the firm said, with no evidence of disease in all patients treated. The data showed all 42 patients in a trial led by Memorial Sloan Kettering Cancer Center in the U.S. had a complete response to treatment, with no evidence of tumors on scans.