Civilization (3000 B.C.E. - 500 C.E.)

Relief of Kubaba

Kubaba of Sumeria becomes humanity’s first female ruler

The Sumerian King List is unsurprisingly filled with the names of men: Alulim, Hadanish, Zizi, and many others. But alongside its male monarchs, the world’s first known civilization also produced a woman who is often considered the first female monarch: Kubaba, who brewed and sold beer in the ancient city of Kish in Mesopotamia. However, some scholars question Kubaba’s historicity, and it is quite possible that there were earlier female rulers we have no record of.

Statuette

Egyptian physician Imhotep diagnoses cancer, perhaps for the first time in history

Imhotep was an Egyptian chancellor to the Pharaoh Djoser, possible architect of Djoser’s step pyramid, and high priest of the sun god Ra at Heliopolis. Very little is known of Imhotep as a historical figure, but in the 3,000 years following his death, he was gradually glorified and deified. In his Pulitzer-prize winning “biography” of cancer – The Emperor of All Maladies – Siddhartha Mukherjee cites the oldest identified written diagnosis of cancer to Imhotep.